Pentapeptide-18/Leuphasyl®’s mechanism mimics in vitro the natural mechanism of enkephalins: it couples to the enkephalin receptor, on the outside of the nerve cells. When Leuphasyl® couples to the receptor, a conformational change initiates a cascade inside the neuron that results in a decrease of its excitability: the nerve cell’s activity is “turned down” and the release of acetylcholine is modulated. Muscle contraction will be relaxed and therefore, expression wrinkles will be diminished.

Pentapeptide-18 - a neuropeptide that gives Botox®- like results, it works synergistically with Argirilene and increases the benefits, reduces the depth stretch marks/ wrinkles caused by the muscle contractions.